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KMID : 0352119960120010083
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Journal of Kyung Hee University
1996 Volume.12 No. 1 p.83 ~ p.87
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A Case of Virus Associated Hemophagocytic Syndrome
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김현희
심계식/차성호/최용묵/최종원
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Abstract
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Virus associated hemophagocytic syndrome is characterized by benign generalized histiocytic proliferation with marked hemophagocytosis associated with systemic virus infection. The syndrome is a nonneoplastic, potentially reversible process and
manifested by fever, severe constitutional symptoms, hepatosplenomegaly, and lymphadenopathy, and characterized by laboratory findings of pancytopenia, hemophagocytosis and abnormal liver funtion test and coagulopathy.
The authors had experienced one case of virus associated hemophagocytic syndrome diagnosed by clinical, laboratory features and bone marrow aspiration. The patient, 4 years old boy, had clinically high fever, mild hepatosplenomegaly,
lymphanoadenopathy
and showed severe pancytopenia in peripheral blood, positive EBV IgM Ab in serum and phagocytizing histiocytes in bone marrow.
A brief review of the literatrues was made.
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KEYWORD
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